NHS Human Services, Inc.

Research Scientist / Postdoctoral Fellow, Environmental and Public Health Sciences Current UC employees must apply internally via SuccessFactors > http://bit.ly/UCEMPL Founded in 1819, the University of Cincinnati ranks among the nation's best urban public research universities. Home to more than 50,000 students, 11,000 faculty and staff and 340,000 alumni, UC combines a Top 35 public research university with a physical setting The New York Times calls "the most ambitious campus design program in the country." With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, nine straight years of record enrollment, worldwide leadership in cooperative education, a dynamic academic health center and entry into the Big 12 Conference, UC's momentum has never been stronger. UC's annual budget tops $1.65 billion and its endowment totals $1.8 billion. The University's overall regional economic impact exceeds $10.6 billion, paving the way for the future of Cincinnati. Job Overview As one of the oldest medical schools in the country, the University of Cincinnati College of Medicine (COM) has a reputation for training best-in-class healthcare professionals and developing cutting-edge procedures and research that improve the health and clinical care of patients. In partnership with the UC Health academic healthcare system and Cincinnati Children's Hospital Medical Center, the College of Medicine's faculty are transforming the world of medicine every day. The Department of Environmental and Public Health Sciences is a top-tier department with world-renowned faculty and staff. A full-time Postdoctoral staff position is available in the laboratory of Dr. Susan Kasper in the Department of Environmental & Public Health Sciences, College of Medicine, University of Cincinnati. The Kasper Laboratory integrates human primary cancer cell culture, cancer stem cell biology, xenograft models, and most recently extracellular vesicles in collaboration with Dr. Somchai Chutipongtanate with multiomics technologies and bioinformatics to investigate mechanisms of prostate cancer progression and metastasis. A leading focus is on mechanisms that drive cancer cell growth and metastasis, in particular cancer cell/tumor microenvironment interactions that regulate these processes via signals carried by extracellular vesicles, and to establish prognostic and predictive biomarkers of metastasis. The successful candidate will play a pivotal role in investigating the molecular mechanisms of prostate cancer metastasis and its interaction with stromal cells in the tumor microenvironment. This position involves a focus on secretomes and extracellular vesicles and utilizing advanced techniques in single-cell sequencing analysis. Essential Functions Conduct cutting-edge research on prostate cancer metastasis, focusing on molecular mechanisms, post-translational phosphorylation, and cell-cell interactions within the tumor microenvironment. Develop and execute primary cell culture (human/clinical specimens) and cell-based studies. Investigate the roles of secretomes and extracellular vesicles in cancer progression Utilize advanced bioinformatics tools and single-cell sequencing technologies to analyze complex datasets. Collaborate with a multidisciplinary team of scientists and researchers. Disseminate research findings through publication in high-impact journals and presentations at international conferences. Required Education Doctoral Degree inMolecular Medicine, Cancer Biology, or a closely related field. Required Experience Experience in primary cell culture from clinical biopsy samples, bioinformatics, including single-cell or spatial sequencing analyses. Excellent analytical, organizational, and communication skills. Strong skills in cell culture and cell-based studie